Erdheim-Chester Disease with a Posterior Fossa Tumour Mimicking Neurosarcoidosis: a Case Report

Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis described in 1930 by Jakob Erdheim and William Chester; it presents as multisystemic entity that forms xanthogranulomas, foamy histiocytes surrounded fibrotic tissue. Lesions are commonly located long bones, central nervous system (CNS), cardiovascular system, lungs, kidneys, skin. The CNS involved approximately 50% of cases can compromise both extra- or intra-axial structures therefore mimic schwannomas meningiomas, among other mass lesions [7, 4]. Clinical presentation will differ from patient to patient; thus, diagnosis depends greatly on imaging, immunohistochemistry, genetic findings within the pathology analysis [8]. pathogenesis this remains unknown. It most found middle-aged male population [1, 2]. Here, we present case woman with an extra-axial lesion was initially considered be neurosarcoidosis proving diagnostic challenge implies.